Immunity to K1 killer toxin: internal TOK1 blockade.

K1 killer strains of Saccharomyces cerevisiae harbor RNA viruses that mediate secretion of K1, a protein toxin that kills virus-free cells. Recently, external K1 toxin was shown to directly activate TOK1 channels in the plasma membranes of sensitive yeast cells, leading to excess potassium flux and cell death. Here, a mechanism by which killer cells resist their own toxin is shown: internal toxin inhibits TOK1 channels and suppresses activation by external toxin

Specific interplanetary conditions for CIR-, Sheath-, and ICME-induced geomagnetic storms obtained by double superposed epoch analysis

The comparison of specific interplanetary conditions for 798 magnetic storms with Dst < -50 nT for the period 1976-2000 was made on the basis of the OMNI archive data.We categorized various large-scale types of solar wind as interplanetary drivers of storms: corotating interaction region (CIR), Sheath, interplanetary CME (ICME) including magnetic cloud (MC) and Ejecta, separately MC and Ejecta, and "Indeterminate" type. The data processing was carried out by the method of double superposed epoch analysis which uses two reference times (onset of storm and the minimum Dst index) and make a re-scaling of main phase of storm a such way that after this transformation all storms have equal durations of main phase in new time reference frame. This method reproduced some well-known results and allowed us to obtain some new results. Specifically, obtained results demonstrate high importance of Sheath in generation of magnetic storms as well as a significant differences in properties of MC and Ejecta and in their geoeffectiveness.Comment: 21 pages, 9 figures, 1 table, submitted to J. of Advances in Space Research on 29 July, 2009 for Special Issue "Space Weather Advances

Etymology of Lexemes of Denoting Colour

Статтю присвячено етимологічному дослідженню лексем на позначення кольору в німецькій, українській та російській мовах. Зроблено спробу порівняти первісні значення кольорів у цих мовах. Проаналізовано лексеми червоний, оранжевий, жовтий, зелений, блакитний, синій, фіолетовий. The article is devoted to the etymologic research of lexemes of denoting colour in the German, Ukrainian and Russian languages. An attempt to compare the primary meaning of colors in the German, Ukrainian and Russian languages is done. Such lexemes as red, orange, yellow, green, blue, dark blue, violet are analysed